Crowe Fukase Syndrome or POEMS is a rare type of blood disorder that gets worse over time and can become very serious if you don’t get it treated. In this you will have a lot of abnormal plasma cells which can destroy your body’s systems and many organs.

POEMS stands for Poly Neurotherapy, Organomegaly, Endocrinopathy, M Protein and Skin Changes. During this disorder, your body produces so many plasma cells that they go out of control.

These cells start releasing monoclonal protein into your blood, which is also called M protein. Exceeding this can cause damage to your nerves and organs. This disease is quite rare and occurs only in people between 50 and 60 years of age. This can happen to anyone, male or female. As the name suggests, it has different parts. So let us know about this disease.

What is POEMS Syndrome?

Poly Neurotherapy: In this, the nerves of your body start getting damaged. This may also cause pain in your hands, legs and other parts of the body.
Organomegaly: In this situation the size of your organ starts increasing. Due to this disorder, the size of your organs like liver and lymph nodes becomes larger than normal.
Endocrinopathy: This is a hormone related problem. During this condition, your endocrine glands start releasing abnormal amounts of hormones.
M protein: When this protein enters your blood, it starts making more copies of plasma cells.
Changes in the skin: In this condition, changes start appearing in your skin like the color of the skin becoming darker, the skin becoming a little thick etc.

symptoms

Its symptoms include weakness, tingling, numbness, burning sensation, feeling as if needles are pricking in the body, enlargement of the liver or lymph nodes, inability to control blood sugar, problems related to thyroid, dark color of the skin. These include thickening of the skin, excessive hair growth on the face and legs, blood vessels appearing like small cherries, etc.

Who does this syndrome affect? mmmm

This syndrome is very rare and very few cases are seen. This can be seen in anyone, male or female. This is mostly seen in people between 50 and 60 years of age. Although it occurs more in men.

Reason

Scientists have not been able to determine the exact cause, although vascular endothelial growth factor may play a role. This factor is also more prevalent in people who have poems syndrome.

Treatment

Radiation Therapy: Direct radiation is used to destroy abnormal plasma cells.
Chemotherapy: Anti-cancer drugs are also used in this therapy so that these extra and abnormal plasma cells can be eliminated.
Physical Therapy: Your doctor can also give you different types of physical therapy which can prove beneficial in eliminating these cells.
Disclaimer: This article is for general information only. It cannot in any way be a substitute for any medicine or treatment. Always consult your doctor for more information.

#diseases caused by m protein #How to avoid thyroid #What is blood disorder POEMS #what is endocrinopathy #What is the function of vascular endothelial growth factor?

Rare problem of POEMS occurs due to abnormal plasma cells reduction, know its symptoms and necessary treatment.

What is POEMS Syndrome?

symptoms

Who does this syndrome affect? mmmm

Reason

Treatment

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