Saturday, May 28th, 2022

Its new variant may be more infectious than Delta, know what experts are saying


New Delhi
For the first time in India, the delta variant of the corona virus is now showing signs of new trouble. Experts are apprehensive that this new variant AY.1 or Delta+ could be more dangerous. It is being told that this new variant is so dangerous that it can even beat the proposed monoclonal antibody cocktail in the treatment of infection.

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New mutation K417N detected
According to Public Health England, an executive agency of the UK Government’s Department of Health and Social Care, the new mutation K417N has been detected with 63 genome deltas. It has been identified by the global science initiative GISAID. In its latest report on Covid-19 variants updated till last Friday, India had reported six cases of Delta+ as of June 7.

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Earlier a similar variant was found in Europe
The report from Public Health England states that the new delta-AY.1 variant was detected through regular scanning of the delta variant. The report reported that a small number of known sequences harbored the spike protein mutation K417N. Scientists said such a sequence had previously been found in Europe in late March.

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Resistance against monoclonal antibodies
Dr. Vinod Sakaria, Clinical and Computational Biologist, Institute of Genomics and Integrative Biology, Delhi, said that the unique thing about K417N is that it confers resistance to the monoclonal antibodies casirivimab and imdevimab. This cocktail of antibodies has been approved by the Central Drugs Standard Control Organization for emergency use in the treatment against the virus in the country.

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There was a report to reduce the effect of the vaccine
Scaria said 127 sequences from Europe, Asia and the Americas are now available in the public domain. Scaria reported that many of the genomes now available worldwide were part of the AY.1 or B.1.617.2.1 lineage. Earlier, a study was conducted by the National Center for Disease Control and the Institute of Genomic and Integrative Biology in which it was found that the delta variant reduces the effectiveness of the vaccine in terms of preventing infection. However, his study also states that the vaccine is still very effective against corona.

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